Flaten, Gøril Eide; Chang, Ting-Tung; Phillips, William T.; Brandl, Martin; Bao, Ande; Goins, Beth (Journal article; Tidsskriftartikkel; Peer reviewed, 2012-12-05)
Context: Camptothecin (CPT) represents a potent anticancer drug. Its therapeutic use however is
impaired by both drug solubility, hydrolysis and protein interactions in vivo. Use of liposomes as
drug formulation approach could overcome some of these challenges.
<p>Objective: The objective of this study was to perform a mechanistic study of the incorporation
and retention of the lipophilic parent ...